Saliva has a significant role in supporting the health of
soft and hard tissues in the mouth. The defensive functions of saliva include
maintaining a neutral oral pH, cleaning and remineralizing the dentition, aiding
swallowing and digestion, and protecting oral tissue. Reduced salivary
secretion can lead to multiple oral problems, such as dental caries, fungal
infections, mucositis, and periodontal diseases. Saliva is also regarded as the
mirror of the body, reflecting the overall
patient's state of health.
Diagnostic Tool
The diagnostic properties of saliva are readily accessible, and the sample collection is non-invasive. A
sample can be tested for proteins,
electrolytes, hormones, antibodies, as well as other substances. The benefits
are even greater when multiple samples over a period
of time are obtained and tested.
Chair-side diagnostic tests and biosensor technologies are
currently under development. These tests can be used to evaluate oral fluids
for disease detection, which will also enable improved access and healthcare outcomes for patients. The detection
of specific periodontal pathogens hidden in a patient’s mouth can promote
treatment planning and risk assessment using hard data, rather than a
subjective assessment.
For example, a saliva test can identify highly toxic bugs
linked with aggressive forms of periodontal disease. The salivary test report
will specifically state which antibiotics will be effective for each bacterial
profile. Patients with periodontal disease can be periodically tested to
determine if the process is active due to various bacteria. The salivary sample
test results can be used to determine a treatment plan that is individualized
for each patient, rather than providing a one-size-fits-all approach.
Future Development
Large-scale clinical trials and independent authentication
studies are needed before noninvasive oral fluid tests become commercially
available for the early detection of oral cancer and other systemic conditions.
Further refinement of oral fluid screening tests to help identify individuals
at increased risk for oral and systemic diseases holds great promise to strengthen
our understanding of the relationship between overall health and oral health.
Dental practitioners can better explain and link the gap
between oral and systemic health by implementing saliva testing. Additionally, the
clinical events and the science of salivary diagnostic testing can have a
positive impact on patient outcomes with minimal to no health risks or
financial concerns for many patients.
Give the dental office of Dr. Steven K. Okamoto a call to
see if you can benefit from Salivary Sample Testing.
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